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By multivariate analysis, only MV was associated with prognosis.
By multivariate analysis, only mechanical ventilation was independently associated with de-escalation (OR 0.25 (95% CI 0.08 0.74), p = 0.023; Hosmer Lemeshow goodness-of-fit test, p = 0.95, c-statistics 0.85).
By multivariate analysis, only three variables remained significantly predictive of the death: personal history of cardiovascular disease (OR 3.1 [1.0–9.4], p = 0.046), the presence of severe sepsis/septic shock in the ER (OR 4.4 [1.3–12.3], p = 0.013), and a PCT level >32.5 µg/L (OR 36.0 [10.0–128.4], p < 0.0001).
Factors associated with an indeterminate result were: CD4 cell count below 300 cells/µl (by both univariate and multivariate analysis), age above 33 years (by univariate analysis only) and male sex (by multivariate analysis only).
By multivariate analysis only co morbidity and critical illness were independent predictors of outcome.
By multivariate analysis only co morbidity and critical illness remained independent predictors of survival (Table 3).
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As seen in Table 3, by using multivariate analysis, only three variables were associated with T. gondii seropositivity: 1) living in a house with soil floor (adjusted OR = 7.16; 95% CI: 1.39 36.84); 2) residing outside Durango State (adjusted OR = 4.25; 95% CI: 1.72 10.49); and 3) turkey meat consumption (adjusted OR = 3.85; 95% CI: 1.30 11.44).
NA: Not applicable * by Fisher exact test In multivariate analysis only the Charlson index [Adjusted Odds Ratio, 1.6; 95% CI, 1.2-2.2; p < 0.0025] and the number of organ failures [Adjusted Odds Ratio, 2.5; 95% CI, 1.15-5.2; p < 0.02] at ICU admission were independently associated with short-term mortality.
However, in multivariate analysis, only MRD assessment by CD160FCA (P<0.01, HR 5.0, Table 2) and Zap-70, status remained independent predictors of EFS (P=0.04, HR 1.90, Table 2).
In multivariate analysis only comorbidities assessed by the Charlson index [Adjusted Odds Ratio, 1.6; 95% CI, 1.2-2.2; p < 0.003] and the number of organ failures assessed by the SOFA score [Adjusted Odds Ratio, 2.5; 95% CI, 1.1-5.2; p < 0.02] were independently associated with 3-month mortality.
In a multivariate analysis only 22% of the variance of UAE could be explained by these variables.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com