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By multivariable analyses, IL-8 and TNFα, but not MIF levels, were associated with the diagnosis of an underlying autoimmune disease.
These trends were observed at 30, 180, and 365 days postdischarge and confirmed by multivariable analyses.
Independent determinants were assessed by multivariable analyses using stepwise backward selection.
Similarly, univariable logistic regression followed by multivariable analyses were conducted to detect independent predictors of MVO disappearance.
Complex samples analysis option was used in statistical package for Social Sciences (SPSS) version 17. Univariate analyses followed by multivariable analyses were carried out.
This was followed by multivariable analyses used to assess the independent effect of each factor after controlling for other related factors.
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After adjusting by the multivariable analyses, the RPF group was independently associated with a lower risk of postoperative AKI, severe AKI, use of renal replacement therapy, shorter postoperative extubation time and intensive care unit and hospital stay.
Notably, we have attempted to address this limitation by performing multivariable analyses.
We evaluated possible effect modification by age category by performing stratified multivariable analyses for patients <15 years versus those 15 years or older, and for patients initially treated with ceftriaxone versus those whose initial antibiotic therapy did not include ceftriaxone.
However, the number of studies are limited and often hampered by either being retrospective or cross-sectional [ 7, 8], or by lack of multivariable analyses in the prospective studies [ 4- 6].
This cohort showed the expected clinical behavior according to both the stratification of the established cytogenetic categories and to the canonical prognosticators by univariable and multivariable analyses (Supplemental Figure S1 and Table S2).
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