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Sigma-2 linduce inducellell death by multiple signalling pathways.
The lifespan of Caenorhabditis elegans is regulated by multiple signalling pathways that converge on a battery of downstream target genes.
MCT1 is a high-affinity transporter and its expression seems to be regulated by multiple signalling pathways, micro-environmental parameters, changes in substrate concentration and pH [ 7].
The inhibitor of cdk activity p27KIP1 is an important example of a protein whose expression and activity is modulated by multiple signalling pathways including steroid receptors.
Sigma-2 receptor ligands have shown efficacy in various tumour cells using cell culture and animal models (Ostenfeld et al, 2005; Kashiwagi et al, 2007, 2009) by multiple signalling pathways.
Epithelial regeneration is driven by multiple signalling pathways, both paracrine and autocrine, that mediate cell-cell interactions within the wounded area and guide regeneration through the distinct phases (Gurtner et al., 2008).
Similar(52)
Accumulating evidence reveals that without activation, CAR forms a protein complex in the cytoplasm where it can be functionally affected by multiple signaling pathways.
For example, Mammalian tooth development is dependent on sequential and reciprocal epithelial mesenchymal interactions mediated by multiple signaling pathways, including BMPs, FGFs, Shh, and Wnt pathways.
This function relies not only on intrinsic material properties but is also determined by dynamic interactions with other cytoskeletal filament systems, distinct cell adhesion sites, and cellular organelles which are fine-tuned by multiple signaling pathways.
The coordinated regulation of pseudopod generation, orientation and persistence by multiple signaling pathways allows eukaryotic cells to detect extremely shallow gradients.
These divergent functions of FoxO proteins are regulated by multiple signaling pathways acting at both the transcriptional and posttranslational levels [47], [54], [107].
More suggestions(17)
by many signalling pathways
by additional signalling pathways
by cellular signalling pathways
by distinct signalling pathways
by physiological signalling pathways
by common signalling pathways
by redundant signalling pathways
by multiple repair pathways
by oncogenic signalling pathways
by active signalling pathways
by multiple endocytosis pathways
by inflammatory signalling pathways
by multiple signal pathways
by multiple transduction pathways
by specific signalling pathways
by canonical signalling pathways
by aberrant signalling pathways
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