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However, the initial genome annotation was submitted by multiple centers using inconsistent methods, making the data difficult to use for many applications.
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One-hundred and forty-six subjects from multiple centers were used to evaluate the accuracy of the Simple Model.
Some centers use multiple compressions over several days.
Some centers used multiple workers to simultaneously collect information at each visit (e.g., separate assessments of mother and child).
In the ICU setting, only four multiple-center studies using the RIFLE criteria have been published so far [ 10- 13].
Three multiple-center studies using conventional statistical models found an association between RIFLE class and mortality [ 10, 11, 13].
This strategy recognizes the data sets with nonlinear separatrix by the multiple centers.
Of these, 186 were found to include multiple centers and/or therapists and were used in our analysis.
We tested heterogeneity between centers by using center as a covariate in the mixed model.
Using samples across multiple centers might overcome this problem but results in inter-center variation.
A large prospective study including patients using BPDS from multiple centers should be conducted.
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