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Inhibitors could be identified by multiple approaches, including enzyme-based screening, viral replication-based screening, structure-based rational design, virtual screening, and fragment-based screening.
Broadly, the main components of the joint research proposal could be: (1) provenance of groundwater and estimation of groundwater recharge by multiple approaches including isotope hydrology, the other methods being hydrogeology, hydrochemistry, piezometric data, and hydrochemistry, and (2) flow, transport and geochemical modelling.
This has been confirmed by multiple approaches, including FN-fibril disruption, reduced adhesion to FN, and loss of "activation" epitopes on integrins (Fig. 2), which all point to "de-activation" of the integrin.
Transfer of recombinant antigen-specific T cell receptors (TCR) and chimaeric antigen receptors (CARs) against tumour and viral antigens are under investigation by multiple approaches, including viral- and nonviral-mediated gene transfer into both autologous and allogeneic T cell populations.
The reliability and efficacy of these cell type-specific classifiers were examined and compared by multiple approaches including a statistical analysis of enrichment of predicted enhancers in the loci of concordantly expressed genes followed by experimental validation of the functional specificity of enhancer predictions using transgenic reporter assays.
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Scientists around the world have paid much attention to the balance between bioenergy production and environmental protection by considering multiple approaches, including the best management practices (BMPs) (Guo et al. 2018; McCalmont et al. 2017a; Wu et al. 2012).
Thus, to maintain an entire bee community, multiple approaches, including maintaining natural habitat, should be implemented.
LOC principals Jeevanjee and Poonam Sharma considered multiple approaches, including adding a single, uninterrupted glass wall to the second story.
RNAi is under development as an insecticide, employing multiple approaches, including genetic engineering and topical application.
Multiple approaches including a crystal seeding study may be useful for this purpose.
The differentiation of activated Müller cells along the photoreceptor lineage was confirmed by multiple approaches that included Hoechst dye efflux analysis [13], genetic analysis using the retina from Nrl-GFP mice [22], and lineage tracing using GS-GFP lentivirus [23].
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