The results of our immunohistochemistry and morphometric analysis as well as testosterone levels in the blood support such a scenario.
The severity of TGF-β1 immunostaining was assessed by morphometric analysis and point counting as previously described [ 10].
Furthermore, the number of LCN2-positive cells per unit area, as determined by morphometric analysis, was significantly greater in FLS as compared to DS mice (P = 0.00028).
These experiments showed that GDNF vector treatment leads to increased rod photoreceptor survival as indicated by morphometric analysis of outer nuclear layer thickness.
Therefore, reduced organelle density and increased area, as showed by morphometric analysis was corroborated by the gene expression pattern of the fusion proteins and led us to conclude that blood feeding induces mitochondrial fusion.
As confirmed by morphometric analysis of the label distribution patterns, our results show that about 80% of labeled fibrinogen and prothrombin, but only 25% of labeled platelets and FXa, accumulated into features of >3100 pixels (Fig. 6C).
Another intriguing pulmonary pathology of Cby−/− mice is the significant increase in airway luminal area as revealed by morphometric analysis (Figure 4), presumably leading to a decrease in airway resistance (Raw) (Figure 9B).
Clusters of significant GM differences among the three groups, as detected by morphometric analysis, are displayed in Figure 1.
Indeed, cBIDKKAA was unable to remodel mitochondrial cristae, as indicated by morphometric analysis of electron micrographs of mitochondria treated with the BID mutants (Scorrano et al., 2002).
We found an increase of glomerular basement membrane thickness in the contralateral db RAS kidney by six weeks post-surgery, as assessed by morphometric analysis of electron microscopic images, a well-recognized feature of evolving diabetic nephropathy.
