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Overexpression of human wild-type FUS restricted to neurons in Drosophila results in a dose-dependent decrease in life span [ 37], and an impaired locomotor phenotype accompanied by morphological abnormalities in motor neurons and neuromuscular junctions [ 8].
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It is characterized by the increased development of distinct morphological abnormalities in the retinal microvasculature that either remains stable or progresses to diabetic macular edema or proliferative diabetic retinopathy, which are leading causes of severe visual impairment in working-age adults especially in industrialized countries [ 7].
As shown in Figure 1E by electron microscopy, exposure to IR induced morphological abnormalities in PBMCs, such as nucleolus fragmentation and the presence of apoptotic bodies.
Using a novel method of visualizing cilia movement, we have determined that the morphological abnormalities in the Tbx6 mutant cilia are accompanied by disruptions in cilia motility.
Consistent with our observations, frequent pupal and larval death because of moulting failure and morphological abnormalities in the testes, antennae, and wings induced by irradiation have been documented in other insect systems [ 73, 74].
Morphological abnormalities in Fn1-null and Itga5-null mutants are obvious by E8.0.
Functional and morphological abnormalities in the mPFC are present in a chronic pain animal model11.
According to a recent study in Brain Research, Prozac-style antidepressants produce some morphological abnormalities in the serotonin nerve network of rats that resemble changes seen with Ecstasy taken in high levels.
Identification of morphological abnormalities in comparison with a healthy tympanic membrane as it is described in standard textbook.
Our objective is to define renal morphological abnormalities in children and adolescents with Fabry disease and minimal proteinuria.
To apply stereology for the detection of possibly morphological abnormalities in placentas of women with intrahepatic cholestasis of pregnancy (ICP).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com