Sentence examples for by modulation of expression from inspiring English sources

It has been postulated that the beneficial effects of EE are mediated largely by modulation of expression of a number of genes involved in neuronal structure, synaptic signaling and plasticity [34] [36].

In addition to the PDE IV activity, this might be explained by modulation of expression of the VIP receptors (VPAC1 and VPAC2) on these cells.

Using this cell line model, we have evaluated the BCAC hypothesis that low-risk SNPs confer breast cancer risks by modulation of expression levels of nearby located genes.

The shifting to the non-replicating persistence state ("dormancy") of the bacteria is accompanied by modulation of expression of genes related to the adaptation to the non-replicating conditions.

To test whether HIF-1 target gene expression was affected by modulation of PHD3 expression we assessed VEGF protein levels.

Since hepcidin down-regulation by inhibitors of 2-OG-dependent dioxygenases was neither mediated by HIF nor by modulation of TfR1 expression, we further speculated that the expression of BMPs may have been altered by the experimental manipulations and may mediate hepcidin regulation.

Hepatitis C virus (HCV) RNA synthesis and protein expression affect cell homeostasis by modulation of gene expression.

This hypothesis implies that in humans it may be possible to promote energy expenditure and treat obesity and metabolic syndrome by modulation of LSD1 expression or activity.

The capacity of the bacterial strains to activate macrophages was assessed by modulation of surface expression of costimulatory molecules CD40, CD80 (B7-1) and CD86 (B7-2) and activation marker Ly-6A/E, and by induction of cytokine production.

Changes in the level of BIN1 isoforms have been linked to tumor progression, which can be induced by modulation of the expression levels of splicing factors [32], [33].

DNA methylation regulates many biological processes, including development and disease by modulation of gene expression.