Sentence examples for by modulation of cell from inspiring English sources
The microglial-astrocyte dialogue was significant and affected microglial cytoskeleton by modulation of cell death and migratory pathways.
The phase-variable expression of these Lewis antigens seems to affect the induced immune response by modulation of cell activation through DC-SIGN.
Besides local tumor control, systemic anti-tumor effects should be induced by modulation of cell death pathways.
The antiproliferative effects of MK-801 arise from cell cycle arrest caused by modulation of cell cycle-regulating gene expression.
In the present study, we confirmed that shikonin significantly inhibited the cell growth and induced apoptosis in A431 cells by modulation of cell cycle and caspase activation through inhibiting the activation of the EGFR NF-κB signalling pathways.
A3AR receptor levels were downregulated on agonist treatment, followed by modulation of cell signaling proteins that belong to the NF-κB signal transduction pathway, resulting in decreased expression of TNF-α and inhibition of the inflammatory process [ 12].
β-defensins are produced directly by epithelial cells, and combat infection both through direct microbicidal action and by modulation of cell-mediated immunity [ 4- 7].
By dephosphorylating PIP3, PTEN may inhibit glioma cell invasion in two ways: by modulation of glioma cell motility by inactivating Rac and Cdc42 as well as by suppression of extracellular matrix (ECM) degradation via MMPs [ 53].
We hypothesized that the anti-angiogenic activity of resveratrol may be caused by modulation of tumor cell release of thrombospondin-1 (TSP1) and vascular endothelial growth factor (VEGF) into the extracellular matrix, leading to vascular endothelial cell (VEC) apoptosis.
Bacterial proteases facilitate pathogen infection by direct host tissue damage, by modulation of host cell signaling and by processing of other bacterial virulence factors [38].
It was thus concluded that receptor downregulation represents receptor functionality and is accompanied by modulation of downstream cell growth regulatory proteins resulting in tumor growth inhibition.
