Sentence examples for by modulating the release from inspiring English sources

BCL2 is a regulator of programmed cell death (apoptosis), in part by modulating the release of proapoptotic molecules from mitochondria.

Therefore, we conclude that CDM reactivated HIV from latency by modulating the release of IL-6 and TNF- α in HIV-1 latently infected U1 cells.

Orexin A actions in the Pa appear to potentiate the stress response, in part by modulating the release of corticotrophin releasing factor (CRF) [ 99- 101].

COX-2 expression decreases the sensitivity of cancer cells to activated antigen-specific T cells by inducing the expression of IL4 and IDO, and by modulating the release of interferon-gamma by activated T cells.

CDM would reactivate HIV from latency by modulating the release of IL-6 and TNF- α, since the amount of both cytokines measured through ELISA significantly increased in U1 treated cells.

To date, it is unknown whether GLP-1 directly suppresses glucagon release by binding to GLP-1 receptors expressed on the alpha cell, or indirectly by modulating the release of secretory products, such as insulin [ 29], somatostatin [ 30- 32], or others, from the beta or delta cells.

The rapid chemical step in these enzymes may be beneficial as it allows control of the aminoacylation rate by modulating the product release step.

These results demonstrated the possibilities of modulating the release profile by means of the processing parameters rather than through the classical approach of altering the formulation.

Previous observations using overexpression and pharmacological approaches suggest that vaccinia enhances its release by modulating the cortical actin cytoskeleton by inhibiting RhoA signalling using the viral protein F11.

Taken together, our data point to a role of cationic channels in the downstream process of unconventional secretion of IL-1β and IL-18, and suggest that in addition to its already described regulatory functions in the cytoskeleton, cell death, and caspase-1 activation, caspase-11 controls IL-1β and IL-18 release by modulating the cationic channel composition of the cell.

CA induced the release of Cytochrome c by modulating the MMP and altering BAX and Bcl2 ratio towards apoptosis.