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By modulating the organization of the actin cytoskeleton, RhoA/ROCK signaling regulates a wide range of cellular functions, such as contraction, motility, proliferation, and apoptosis.
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Whether CENP-V exerts its effect on centromeric architecture indirectly through effects on the chromosomal passenger proteins or more directly by modulating the formation or organization of pericentromeric heterochromatin remains to be determined.
By modulating the spatiotemporal pattern of actin organization, they are capable of switching between different modes of interaction with a particle, either arresting at a concave region and applying force in an attempt to sever the particle there, or extending the cup along the particle surface to identify the very end of the object to be ingested.
We conclude that manganese regulates cytoskeletal organization in astrocytes by modulating the activity of p115RhoGEF and RhoA.
The system works by modulating the LED lighting in your home or office.
In turn, filament number could be controlled by modulating the activity of filament nucleators, cappers or depolymerizers, while actin organization could be regulated by filament crosslinkers, bundlers or motor proteins.
Chromatin organization also plays a role in transcriptional initiation by modulating the accessibility and positioning of both cis- and trans-regulatory elements.
Hallucinogenic drugs are thought to work largely by modulating the prefrontal cortex, tricking the brain into believing that its sensory delusions are revelations.
Sensitivity is enhanced by modulating the electric field.
By modulating the sound, that pocket can be moved around, changing the position of the bead.
By modulating the flux through the loop,the cavity frequency is modulated.
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