Sentence examples for by modulating the matrix from inspiring English sources

The increase in growth after the addition of follistatin antibodies in vitro, or the direct inhibitory effects of recombinant follistatin on glioma proliferation might hence influence important cell maintenance signals or directly impact cell proliferation e.g. by modulating the matrix.

However, in the delayed phases after injury, MMPs and other proteases may also play beneficial roles by modulating the extracellular matrix (ECM) and trophic factors in the brain parenchyma and at the neurovascular interface [11], [17].

Imaging further suggested that the neutrophils aided the invasive process into the tissue by modulating the collagen matrix (He et al., 2012).

Moreover, ectopic expression of BM742401 significantly decreases cellular invasion and migration in part by modulating the activity of matrix metalloproteinases.

RNR might also control the kinetics by modulating the electronic coupling matrix element between the iron sites and these amino acids.

It is also likely that external signals can alter O2− production through the post-translational modification of the respiratory chain, or by altering H2O2 efflux from mitochondria by modulating the activity of matrix peroxidases such as peroxiredoxins.

A cell responds to matrix by modulating the amount and distribution of matrix-binding membrane proteins and reshaping the cytoskeleton structure.

On the other hand, there are available data clearly challenging the classic dogma stating that MMPs promote metastases exclusively by modulating the remodelling of extracellular matrix.

This association could be relevant because it is now known that MMPs promote metastases not only by modulating the remodelling of extracellular matrix, but because MMPs are able to impact in vivo on tumor cell behaviour as a consequence of their ability to cleave growth factors, cell surface receptors, cell adhesion molecules, and chemokines/cytoquines [ 30- 33].

Because both monomers in the PEGDMA- co-EGDMA system undergo cross-linking reactions, tuning of the matrix stiffness is realized by modulating the ratio of the high molecular weight PEGDMA monomer relative to the low molecular weight EGDMA monomer.

Heparan sulfate also can act indirectly in the system, e.g. by modulating the processing of growth factor precursors by matrix metalloproteases [25].