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Bi-VSP injected through the stinger induces a lethal melanization response in target insects by modulating the innate immune response.
Phytochemicals have also proved to enhance immunity by modulating the innate and adaptive immune responses.
It seems that estrogen can have powerful immunomodulating effects, albeit mainly during stress, by modulating the innate immune response (Kovacs et al 2004; Kovacs 2005).
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We provide evidence that the aqueous extract of O. stamineus leaves protect the host from infection by modulating the host innate immune response towards S. aereus.
In this study, we uncovered a role of LRRK2 in modulating the innate immune response in macrophages.
It has been suggested to suppress the development of inflammatory helper T cells modulating the innate immune system [[82]].
Endogenous GCs play a critical role for modulating the innate immune response in the CNS.
68, 69 T-bet also controls adaptive immune responses by modulating the function of innate immune cells, including dendritic cells.
In addition to direct effects on beta-cell numbers and function and glucose-insulin balance, environmental chemicals may affect T1DM development by modulating the function of innate and adaptive immune cells.
Recently, Zhang et al. (2011) showed that bacteria-responsive plant microRNAs regulate plant innate immunity by modulating the plant hormone network [ 7].
KIR molecules operate in both adaptive and innate immunity by modulating the development and activity of natural killer (NK) and T cell subsets through differential interaction with specific major histocompatibility complex (MHC) class I molecules on target cells.
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