Sentence examples for by modulating the activation from inspiring English sources

Thus, a Cav-1 deficiency profoundly affects mammary epithelia by modulating the activation state of important signaling cascades.

Our recent study also demonstrated that LBP protect RGC by modulating the activation of microglia in an animal model of chronic ocular hypertension [65].

We propose that 2 5 μM 2-APB enhances progesterone-induced Ca2+ influx by modulating the activation by STIM of channels incorporating Orai.

First, ductal growth stimulation, whether lateral branching or end bud extension, probably shares mechanisms designed to inhibit TGF-β action locally, possibly by modulating the activation of latent growth factor.

It is therefore possible that the kynurenine pathway, by modulating the activation and blockade of NMDA receptors, is involved in these early stages of brain development in the embryo.

Stimulators, such as cytokines, control the expression of MMP-9 by modulating the activation of AP-1 and NF-κB through Ras/Raf/ERK, JNK, and PI-3 K-AKT/PKB signaling pathways [ 9, 14, 18, 19].

We demonstrate that the loading of heterologous proteins to the 1,2-propanediol utilization microcompartment of Salmonella enterica can be controlled using two strategies: by modulating the transcriptional activation of the microcompartment container and by coordinating the expression of the microcompartment container and the heterologous cargo.

Sex hormone levels may play a role because these have been associated with the incidence of depression and may also influence stress reactivity by modulating the maturation, activation and feedback of the HPA axis [ 65– 65].

Our studies provide potential novel neurotherapeutics for the management of glaucoma by modulating the EAAT1 activity via gene activation.

Distinct mechanisms have been reported to induce MOMP by modulating the expression and/or activation of the various pro- and anti-death BCL-2 family members in conditions of unresolved ER stress.

In summary, as the EDA pathway is a hot spot of adaptation [ 22], it is easy to imagine that by modulating the level of activation of the EDA pathway through space and time, the regulation of these two isoforms (and especially A) could follow or sometimes allow rapid evolution of ectodermal appendages.