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Using this approach, we demonstrate that soft ECMs render cells maximally sensitive to changes in RhoA activity, and that by modulating the ability of cells to engage and contract soft ECMs, we can dynamically control cell spreading, migration, and matrix remodeling.
Changes in the yeast phenotype stimulated by FA may be due to the disruption of an existing protein interaction, by changing the stability of the protein (or), by modulating the ability of the protein to interact with other molecules, (or) by initiating a series of signal transduction pathways upon binding to a particular protein.
Similarly, the context of an ORF or uORF stop codon can exert general effects on translation by modulating the ability of the ribosome to reinitiate after termination and translate downstream ORFs [ 26].
The most prominent viral genetic association with outcome of therapy is that HCV genotype 1 is much less sensitive to treatment than genotypes 2 and 3, but genetic differences below the genotype level also influence outcome of therapy, presumably by modulating the ability of viral genes to blunt antiviral immune responses.
One possible explanation is that regulatory T cells (or factors) are present in the cultures and suppress Tck effector function, either by modulating the generation of effector Tck cells and/or by modulating the ability of the monocytes to produce TNF-α after contact activation [ 39].
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Our results indicate that the mosquitoes asymptotic spreading speed can be controlled by modulating the invasive ability of winged mosquitoes.
As a result, it is strategically positioned to influence P450 activity by modulating the electron donating ability of the thiolate.
Having established a measurable relationship between the kinematics of the movements being viewed and the readability of intentions in those movements, we asked whether it would be possible to improve the ability to detect intention by modulating the expression of kinematic features.
The ability to manipulate the electron in phase-space can be extended by modulating the amplitude and frequency of the HCPs.
One dimensional cavities were designed by modulating the lattice constant.
Sensitivity is enhanced by modulating the electric field.
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by modulating the function
by modulating the amount
by modulating the acetylation
by modulating the laser
by modulating the length
by modulating the measurement
by modulating the potential
by modulating the production
by modulating the induction
by modulating the sound
by modulating the porosity
by modulating the flux
by modulating the outcome
by modulating the grating
by modulating the barrier
by modulating the diffusion
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