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This malleability is achieved by modulating subsets of genetic, molecular and cellular mechanisms that influence the dynamics of synaptic connections and neural circuitry formation culminating in gain or loss of behavior or function.
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Thus it is understandable that CREB3 subfamily transcription factors might serve different physiological roles in their target cells by modulating distinct subsets of genes in response to specific stimuli.
The effect of DBS entered the models by modulating a subset of connections.
Monocyte-derived DCs required the expression of MHC-II to promote this effect, suggesting that they interacted with antigen-reactive T cells directly, rather than indirectly by modulating another subset of DCs.
These novel findings show that the nutritional environment during early post-natal development controls the capacity of the adipocyte to accumulate fat by modulating the expression of a subset of genes associated with the structure of caveolae and that this capacity for structural remodeling is recapitulated in the adult mouse depending upon the nutritional environment.
A recent study has shown that a Wnt signaling pathway may be involved in maintaining synaptic strength in the CNS by modulating the translocation of a subset of acetylcholine receptors (AChRs) to synapses [ 38].
Therefore, by modulating the expression of specific genes, the differentiation of stem cell can also be modulated through manipulating the key transcription factors [16, 17].
By means of a well-designed square window function, we here propose the concept of continuous subset in order to modulate subset size in a continuously derivable manner.
Microtubules can undergo phases of growth and shrinkage by modulating dynamic instability; however, stabilization of a subset of microtubules is necessary for cell motility [ 4] and morphogenetic events [ 5].
KIR molecules operate in both adaptive and innate immunity by modulating the development and activity of natural killer (NK) and T cell subsets through differential interaction with specific major histocompatibility complex (MHC) class I molecules on target cells.
The FOXP3 gene controls the differentiation of lymphocytes into regulatory T lymphocytes (Treg), a subset of T helper cells that inhibit atherosclerosis by modulating lipoprotein metabolism [ 17].
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