The algorithm was used to generate both in vitro and in vivo evoked LFP and reflected the changes seen during LTP and LTD, when such changes were induced in the underlying neurons by modulating release probability of synapses and sodium channel regulated intrinsic excitability of the cells.
Orexin A actions in the Pa appear to potentiate the stress response, in part by modulating the release of corticotrophin releasing factor (CRF) [ 99- 101].
COX-2 expression decreases the sensitivity of cancer cells to activated antigen-specific T cells by inducing the expression of IL4 and IDO, and by modulating the release of interferon-gamma by activated T cells.
CDM would reactivate HIV from latency by modulating the release of IL-6 and TNF- α, since the amount of both cytokines measured through ELISA significantly increased in U1 treated cells.
BCL2 is a regulator of programmed cell death (apoptosis), in part by modulating the release of proapoptotic molecules from mitochondria.
To date, it is unknown whether GLP-1 directly suppresses glucagon release by binding to GLP-1 receptors expressed on the alpha cell, or indirectly by modulating the release of secretory products, such as insulin [ 29], somatostatin [ 30- 32], or others, from the beta or delta cells.
Antipsychotic drugs could affect glutamatergic neurotransmission by modulating the release of glutamate, by interacting with glutamate receptors, or by altering the density or subunit composition of glutamate receptors (Goff and Coyle, 2001).
Therefore, we conclude that CDM reactivated HIV from latency by modulating the release of IL-6 and TNF- α in HIV-1 latently infected U1 cells.
These medications act by inducing mobilization of hematopoietic stem cells and by modulating production and release of neutrophils into peripheral blood.
These findings support the concept that the neuroprotective effect of DMF is exerted on neurons directly at pre-synaptic terminals by modulating glutamate release, and indirectly at post-synaptic level, by modulating microglia function in a dose-dependent manner.
