Sentence examples for by modulating mitochondrial function from inspiring English sources

The mitochondrial prohibitin complex was suggested to affect longevity by modulating mitochondrial function and fat metabolism in C. elegans in a genetic-background-specific manner [6].

In a study of the nematode Caenorhabditis elegans, prohibitin complex was shown to promote longevity by modulating mitochondrial function and fat metabolism [ 17].

H2O2 has a major role in modulating mitochondrial function by inhibiting activities of the mitochondrial enzyme in a fully reversible fashion [3, 4].

An increasing number of genetically-engineered and aging rodent models are shedding additional light on the mitochondrion's role in regulating glucose metabolism and insulin sensitivity by modulating mitochondrial morphology, function and quality control pathways.

Finally, strategies to limit the extent of renal mitochondrial damage during hyperglycemia (by therapeutic agents that will specifically modulate mitochondrial function) might prevent or inhibit the development of nephropathy in the diabetic population.

NO is known to modulate mitochondrial function, generally downregulating mitochondrial energy production by reversibly inhibiting cytochrome c oxidase, the terminal acceptor in the mitochondrial electron transport chain [ 45].

There has been increasing interest in the development of tools that modulate mitochondrial function, and the refinement of techniques that allow for real time monitoring of mitochondria, particularly within their intact cellular environment.

In their turn, superoxide flashes modulate mitochondrial function, as they cause mitochondrial depolarizations.

Taken together, these results suggest that Clu directly modulates mitochondrial function, and that Clu's function contributes to the PINK1-Park pathway of mitochondrial quality control.

Through intranuclear translocation, the RTG proteins induce the transcription of specific target genes, which in turn modulate mitochondrial function.

At subcellular level, NO was shown to modulate mitochondrial function through reversible and irreversible interactions with respiratory chain complexes.