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In addition, C. cellulovorans optimizes carbohydrase production by modulating expression of metabolism-associated genes encoding cellulosomal and non-cellulosomal enzymes, depending on the availability of polysaccharides (Matsui et al. 2013; Aburaya et al. 2015; Esaka et al. 2015).
Furthermore, ECT2 knockdown inhibited cellular proliferation in vitro by arresting cell cycle progression at the G1 phase by modulating expression of cell cycle-related molecules, which ultimately leads to inhibition of cyclin D1-CDK complex activity.
It has been reported that telomerase may promote cell proliferation by modulating expression of growth-controlling genes, such as EGFR, FGF and IL-1Ra [ 8].
The ERFs are secondary ethylene activated factors, which increase plant tolerance to stress by modulating expression of downstream stress-responsive genes [ 65].
The host cell gears up its arsenal on receiving signals of pathogen attack through elaborate signal transduction network by modulating expression of several transcription factors.
By modulating expression of a CENH3-GFP reporter cassette using different promoters, we isolated two reporter lines that allow for a clear and highly specific labeling of centromeric chromosome regions in somatic and gametophytic cells respectively.
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We hypothesize that BRCA1 confers tissue-specific tumor suppression by directly modulating expression of a set of breast-cancer-related genes.
ANP32A (LANP) regulates neuronal differentiation by epigenetic modulating expression of the neurofilament light chain, an important neuron-specific cytoskeletal gene [ 22].
Our findings indicate that miR-18a acts as an oncogene and plays a role in gastric adenocarcinogenesis, at least in part by negatively regulating PIAS3 and thereby modulating expression of STAT3 target genes.
Thus, it appeared that lunasin exerted synergistic effects imposed by the selected cytokine IL-12 or IL-2 on modulating expression of target genes in NK cells.
In Arabidopsis thaliana, the miR156-SPL module regulates the formation of (E -β-caryophyllene in thE -β-caryophyllenethrough modulating E -β-caryophyllenesesquinerpene synthese gene TPS21.
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