Sentence examples for by modulating cell adhesion from inspiring English sources
Our knowledge of the in vivo roles for Rnds has come from work conducted with the Xenopus homologue xRnd1 which was found to regulate morphogenetic movements by modulating cell adhesion in early embryos [15].
Anosmin-1 may also enhance the invasion of tumor cells within the ECM by modulating cell adhesion and activating extracellular proteases.
In this study adhesion and migration parameters were measured separately and thus represent independent, quantitative parameters that will help to achieve a better understanding of the complex relationship between adhesion and migration, and could be used to identify potential therapeutic agents that promote cell migration by modulating cell adhesion (lower or higher).
In addition, uPAR is capable of modulating cell adhesion by activating cells directly via a G-protein-coupled receptor (Liu et al, 2002), by sequestering caveolin (Wei et al, 1999), and by affecting intracellular signalling events (Nguyen et al, 1999).
PAI-1 contributes to cancer dissemination by preventing excess degradation of the extracellular matrix, modulating cell adhesion [ 39], promoting tumour angiogenesis [ 40] and stimulating proliferation [ 41].
We show that FLRT3 and Unc5B functionally interact in modulating cell adhesion during early Xenopus development, and provide evidence that the Unc5B effect on adhesion is mediated by Rnd1.
To investigate whether RRM2 plays a role in modulating cell adhesion in CRC, we developed a real-time cell adhesion assay based on the RT-CES® system.
Plasmin can modulate cell adhesion by directly digesting tenascin as it has been shown in lymphocytes [ 36].
The uPA/uPAR system does not only support the invasion of tumor cells, it also modulates cell adhesion by interactions of uPAR with vitronectin and integrins.
Second, when PAI-1 is bound to the plasminogen activator, it is able to modulate cell adhesion by decreasing its affinity for vitronectin and increasing its affinity for endocytic receptors, thus enabling cell migration.
