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Al has also been shown to impact root growth by modifying the levels of phytohormones such as auxin [ 89] and ethylene [ 8].
This would predict that lengthy exposure to the drug will influence translation by modifying the levels of initiation and elongation factors.
In addition, by modifying the levels of the receptors, we created two additional models: mIL-6R+/sIL-6R−, obyained by specifically inhibiting IL-6TS in LNCaP and Du145 cells by sgp130; and mIL-6R−/sIL-6R+, in which the sIL-6R has been added to the cells after knockdown of both soluble and membrane IL-6Rs.
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Interestingly, this effect can be also obtained in our case by modifying the level of depression (note that in the present study we use a logarithmic scale for the frequency domain, which indicates that the second resonance peak is in fact a very broad peak).
Thus, the activity of MRFs can be regulated by modifying the level of the MRF or one of its partners.
Activity altering polymorphisms in FasR (−1377G > A and -670A > G), FasL (−844 T > C) and CASP8 (−652 6 N ins/del) genes have been shown to alter the mechanism of apoptosis by modifying the level of expression of their correspondent proteins.
By modifying the pH level that triggers this response, R bodies become a tunable platform for controlling release of toxins or therapies.
Here, we revisit the Bi2212 phase diagram by modifying the doping level of the as-grown crystal, by annealing in situ cleaved samples either in vacuum, resulting in homogeneous underdoping, or in ozone, resulting in overdoping of the near-surface region.
It is possible to modify drug release of tablets by modifying the wax level and excipient type of the formulation.
By modifying the expression level of endogenous miR-17, the function of canonical Wnt signaling was reversed.
Several methods have been developed to engineer the cellular metabolism by modifying the expression level of genes coding for enzymatic steps that are considered either rate-limiting or diverting the metabolic flow towards by-products.
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