Sentence examples for by modifying the dose from inspiring English sources

There is also the possibility of further reducing de Gramont drug costs by modifying the dose.

Our findings are in accordance with previous studies showing that the presence and length of treatment-free intervals are major determinants in the development of drug resistance in tumour cells, and that drug resistance acquisition can be hindered, prevented and even circumvented simply by modifying the dose and schedule of chemotherapy administration [ 1, 19, 20].

In a study by Gelman and Taylor (1984), the age-related increase in toxicity with CMF was eliminated by modifying the doses of methotrexate and cyclophosphamide based on renal function, and empirically decreasing the dose of 5FU by two-thirds.

Furthermore, by modifying the doses of XP to manage adverse reactions, XP could be one of the standard regimens for the first-line treatment of unresectable advanced or recurrent gastric cancer in Japan.

Side effects of diarrhea might require modifying the dose.

Electroacupuncture (EA) is a modified form of acupuncture, which consists of passing an electrical current through needles into the acupoints and controls the acupuncture dose by modifying the frequency and intensity of stimulating currents.

Different shapes could be made by modifying the basic geometry.

Very high doses of propofol seem to directly inhibit the activity of complex IV and uncouple the respiratory chain by modifying the structure of F1F0ATPase.

Timing and dose-controlled exogenous hormone supplementation aimed at normalizing melatonin levels have been shown to affect the circadian pacemaker by modifying the internal clock in humans.

Therefore, it is prudent to modify the dose of ESA to reduce the likelihood of excursions of Hb exceeding 13 g/dl as recommended by the NKF (51).

The safety committee could modify the dose-escalation plan by adding patients, intermediate dose-levels and supportive care therapies or by adjusting the combination agent dose, as appropriate according to the accruing safety data.