Sentence examples for by modifying the activity from inspiring English sources

Exact(13)

Transcriptional activation of a number of IFN-inducible genes was rapid and independent of new protein synthesis, indicating that IFNs activated transcription by modifying the activity of pre-existing proteins and transcription factors.

Thus, oncogenic activation can also interdict TGFβ growth inhibitory responses by modifying the activity of downstream elements such as cell cycle inhibitors or transcriptional cofactors of Smad transcription factor activity.

They made the surprising discovery that the virus was only the indirect cause; it triggered the cancer by modifying the activity of a gene already within the cells.

By modifying the activity of extracellular matrix proteases, wound healing in the damaged ocular surface may proceed in a favorable or unfavorable manner, depending on the timing and duration of intervention.

Given that T-cells express PPARα and PPARγ, these PPARs can influence the adaptive immune system by modifying the activity of these cells (Marx et al., 2002).

Experimental studies have now proven that it is indeed possible to transform a cell in culture by modifying the activity of only a few critical genes.

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Similar(47)

To date, molecular breeding for K use efficiency is mainly attained by modifying the activities of K channels and transporters that mediate K uptake, redistribution, and cellular K+ homeostasis.

Most evidence to date on the role of central epigenetic processes in alcoholism has been collected from studies focusing on histone acetylation, often by modifying the activities of the enzymes that add acetyl groups (i.e., histone acetyl transferases [HATs]) or remove acetyl groups (i.e., histone deacetylases [HDACs]).

Using this knowledge we have recently designed targeted optogenetic approaches to detect seizures at their onset, and then in real time disrupt them by instantly modifying the activity of key elements in the epileptic circuit.

Late stages of fusion were affected by PtdIns(4,5) P2-targeting reagents and by modifying the functional activity of dynamin either by expressing different dynamin mutants or by blocking dynamin GTPase activity with cell-membrane-permeant inhibitors.

An alternative hypothesis is that NIBS induces beneficial effects by modifying the distributed activity and connectivity in functional brain systems.

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