Sentence examples for by modifying cell cycle from inspiring English sources
For example, matrix metalloproteinases may act in transformation by inducing apoptosis in anchorage-dependent cells and/or by modifying cell cycle checkpoints through alterations in cell adhesion.
Recent study has demonstrated that an altered peptide ligand derived from HSP60 induces the activation of T cells by modifying cell cycle phase's distribution of CD4+ T cells from RA patients [ 26].
This is achieved most likely by modifying cell cycle and transcriptional regulation, for instance, the infection of cabbage leaf curl geminivirus (CaLCUV) has been shown to induce changes in the cell cycle in virus infected cells [ 47].
While there is evidence that RB and p53 function in related/partially overlapping pathways to modify cell cycle checkpoints, this point remains unresolved and is likely modified by discrete forms of DNA damage.
Cell cycle studies on ET-743-treated BTC cells, demonstrated that the chemotherapy acts by modifying the cell cycle status, mostly inducing an increase of sub-G0 phase cell fraction and triggering apoptosis as preferential mechanism.
These hypotheses make different predictions about the outcome of modifying cell sizes by transiently perturbing cell-cycle progression: parallel control would perpetuate altered cell sizes, whereas feedback would correct them [ 4].
These classes of hepatocytes arise as the result of modified cell division cycles.
The identification of the molecular targets that are affected by SIRT1 phosphorylation, especially at sites modified by cell cycle-dependent kinases like Cdk1, will help to elucidate how changes in the level and activity of SIRT1 affect diverse processes such as growth and longevity in organisms ranging from single-celled yeast to mammals.
Tumor development occurs when a cell accumulates genetic alterations that modify normal cell cycle progression.
Treatment with an anti-luciferase siRNA control did not modify the cell cycle profiles.
The depletion of MBD4 did not significantly modify the cell cycle distribution of untreated HeLa cells (Fig. 4A).
