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ERα has also been shown to play a role in AI resistance, in the form of a constitutively active ligand-independent mutant ERα [ 36], via different genome binding patterns [ 37], or simply by modified expression levels [ 38].
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Our group is currently generating transgenic plants with modified expression levels for these genes to confirm the hypothesis raised for their function.
These changes were paralleled by increased expression levels of CD36.
Relative expression levels were calculated by dividing RAE1 expression levels by UBQ expression levels.
Cellular redox homeostasis is also directly regulated by p53 through modified expression of pro- and anti-oxidant proteins.
Expression levels were simulated by randomly selecting recorded expression levels.
Physcomitrella protoplasts transfected with the single 35S promoter and the 35S long) promoter, including this modified sequence around the ATG, showed increased expression levels by about 52% and about 33%, respectively (Fig. 4).
In addition to the effect of the –NH2-modified surface, the –OH- and –COOH-modified surfaces caused increases in the expression levels of Cbf α-1 and ALP on certain days.
The culture conditions, including the culture media, temperature, agitation speed and air flow were tested in order to obtain an increased expression levels of the modified protein.
Differences in measured levels of protein modifications may be due to changes in both the modification stoichiometry and expression levels of the modified protein.
This shows that cbfa1/runx2 responds to reduced gravity by expression level changes in vivo.
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