Further evidence for the role of the dNTP γ-phosphate in binding and positioning of the dNTP for DNA synthesis has been provided by mutation of the K65 residue to abolish the interaction [5] and by modification of the nucleotide γ-phosphate [20].
The second one is the modification of task scheduling (timing, prioritization, and duration); and the third way concerns modification of the interaction by providing different styles, amounts of data, and interface features.
Although we found no significant evidence overall of modification of the interactions by race, the finding that African Americans show apparently less pronounced interactions bears further investigation.
The regulation of the mechanical stability of GB1 by IgG fragments is not through direct modification of the interactions in the mechanically key region of GB1; instead, it is accomplished via the long-range coupling between the IgG binding site and the mechanically key region of GB1.
This indicated that sublytic concentrations of suilysin also contributed to pathogenesis by modification of host-pathogen interactions (Seitz et al., 2013).
First, an effect of modification by the interaction of obestatin (and probably of some similar molecules, participating in uremic milieu) with TNF- α may explain, at least in part, the existing conflicting data linking elevated circulating TNF- α levels to all-cause and cardiovascular mortalities in maintenance HD patients [ 26, 27].
This will result in the modifications of the exchange interactions.
Furthermore, we used the case-only approach to determine the statistical significance of effect modification by testing the interaction between temperature and individual characteristics of interest.
There was no evidence for modification of the sex interaction by diabetes, age, obesity (data not shown), or when grouped into presumed premenopausal (<50 years old) and postmenopausal age (≥65 years old).
In this article, the authors present a logical model of protein-protein interactions that allows to take into account the modifications induced by the interaction at certain residues.
