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This can be achieved by modeling the structure of mutants computationally and by performing molecular docking simulations.
We further demonstrate the utility of the PCAIN protocol to derive biological insight into protein structure-function relationships, by modeling the structure of the YopM effector novel E3 ligase (NEL) domain from plague-causative bacterium Yersinia Pestis and discussing its implications for host adaptive and innate immune modulation by the pathogen.
Yet, in the recent years, many statisticians have made great attempts to develop statistical approaches for estimating ODE parameters by modeling the structure of measurement errors [ 35- 42].
We tested this hypothesis by modeling the structure of pol γ-β from these two species and that from D. melanogaster and C i. intestinalis (control species that lack completely the HLH-β3 element).
The related rotational echo double resonance (REDOR -taxol stREDOR -taxolpropostructureima in 2005 based on initial REDOR experiments reported in 2000 by Bane et al. The structure was modified by a second set of REDOR NMR data and by modeling the structure in a reshaproposed tubylin structure.
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The relationship between the structures and the activities of the variants were analyzed by modeling the structures of the endoglucanase II variants.
For the monomeric form, the structural coordinates for decoron corresponding to 1XCD were modified by modelling the structure of the missing N and C-terminal amino acid residues (1 21, 327 330) of one of the two molecules found in the dimeric form to create one full length decoron molecule.
Transient acoustic radiation from transverse vibrations of beams and beam-like structures is obtained by modelling the structure as a series of contiguous dipoles.
The simulations are made by modelling the structures with Monte Carlo FLUKA code, dividing cosmic rays into 5 ionic groups.
By modeling the chromatin structure using high-resolution chromosome conformation capture data and mapping the methylation level onto the modeled structure, we demonstrated that the patchiness of DNA methylation is related to chromatin structure.
This is accomplished in part by modeling the course structure around scientific methodology (discussed in greater detail below).
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by modeling the structures
by modeling the way
by analysing the structure
by manipulating the structure
by modeling the product
by modeling the background
by modeling the space
by modeling the inter-crossover
by modeling the course
by modeling the selection
by modeling the distance
by modeling the variance-covariance
by modeling the pattern
by modeling the exposure
by modeling the transition
by modeling the time
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