Clean data are prepared through running a Thomas' river water quality model and polluted data are synthesized by mixing clean data with white Gaussian noises.
Further validation was provided by mixing the original data among the tasks as follows.
By using area groups we avoid problems caused by mixing data from cells having different nuclear area (18), and we can compute our features from the area groups that contain most of the prognostic information (10, 18).
Techniques for the predicting of synthetic lethal interactions have had some success by mixing heterogeneous biological data [ 25, 26]or by exploiting the topology of the underlying protein interaction network [ 21, 27].
To estimate the sensitivity of the detection pipeline and infer the total number of pSNMs in clinically unremarkable individuals, we performed a computer simulation to generate ∼20 000 simulated mosaic sites each at varied minor allele fractions by mixing the real sequencing data (see Materials and Methods).
To evaluate the performance of our pipeline, we generated a benchmark data set of simulated mosaic and polymorphic sites in silico by mixing the whole-genome sequencing data from two individuals (the " in silico mixture dataset"), according to Cibulskis et al. We selected two individuals, NA12878 and NA12891, for whom the sequencing depth was similar to our samples.
Recently, there have been a large number of attempts to solve diagnosis problems by mixing low-level and high-level data.
To assess the impact of combining DARA with these combination chemotherapies, we prepared cocktails of these agents, by mixing them at concentrations causing ±30% of the maximal lytic effect on various MM cell lines (data not shown).
"I think one issue in the past was that they compared a lot of people by mixing different laboratories, different devices, and including data from patients, so the entire thing was not standardised," Cajochen said.
Here we explore this aspect of SCFG-based infirstly, firstly by evaluating whether mixing on visible states in our data set is confounded by mixing in latent space; and secondly by permitting mixing to be dependent on both visible and hidden states, such that mixing becomes a dynamic component of the recruitment process.
