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Our investigation found that many reviews were affected by missing data on harms from at least one eligible study.
The value of RRMSE was caused by missing data on the number of workers at the loop and on the actual gutter speed level.
Our results may have been severely compromised by missing data on some risk factors.
Bias might have been introduced by missing data on clinical parameters and therapy.
12 The data available on outcomes are limited by missing data on birth weight, sex and particularly gestation.
However, it has been estimated that only 2% of Danish HCV infected patients have been treated with interferon, 60 and therefore we find it unlikely that the results are substantially confounded by missing data on antiviral treatment.
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Whether estimates are biased by missing data depends on the relationships between the chance of data being missing and the variables involved in the analysis.
By contrast, many missing data on just one or a few tests may indicate that such data will end up missing in practice too, so imputation and incorporation of such a test in a prediction rule seems unwise.
The study was affected by missing data.
Two hundred and sixty-six (30%) of the 894 patients, not recorded as having died by 28 days, were missing data on all postdischarge health and social care contacts.
We did not use data imputation and excluded cases with missing data on analysis-by-analysis basis (unless mentioned otherwise).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com