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Matching gene-expression and miRNA profiles of 215 sporadic breast cancer specimens were obtained by mining a microarray dataset described by Buffa et al. [ 23], in GEO (Accession number GSE22220), samples BCmicroRNA 1 to 110).
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By mining the data from several validation datasets it was possible to determine which factors contribute to the variance in normalized DNA-microarray data.
We hypothesized that genes under the control of CBP60g and SARD1 could be identified by mining public gene expression data for genes co-expressed with the 45 genes whose expression was found to be suppressed in cbp60g, sard1 or cbp60g sard1 mutant plants using a small defence-related custom microarray (GEO: GSE18865 [ 20]).
The initial set of genes extracted from each source will be further extended from a source specific network, once by utilizing a microarray based network and the other by utilizing a text-mining based network, by including their direct neighbors for further analysis.
By data mining in microarray datasets we found that expression of DLX2 occurred in 21.6% of patients, and was significantly correlated with prolonged disease-free survival and reduced incidence of relapse.
Expression data for a time course of asexual development was mined from microarray data (Greenwald et al. 2010).
Here the expression profiles of the six OsRUS genes were data-mined from microarray, EST and MPSS publicly available databases and generated by qRT-PCR approach, respectively.
By mining data from our prior microarray study [ 47], reliable signals were obtained for 221 ePK genes in one or more of the three developmental stages.
Here it is shown that gene set analyses provides a simple, yet effective, method by which to mine microarray data.
The heat map was produced by mining out only the 7,539 H. glycines microarray probe sets on the Affymetrix® soybean GeneChip®.
Thus instead of identifying disease related or drug related genes from an expert-curated source, we will be utilizing text mining and microarray data as genes associated with a complex disease pathway are not all identified.
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