However, previously published tumor xenograft studies in nude mice revealed that interactions between cancer cells and activated stromal cells resulted in larger tumors, compared to cancer cells plus normal nonactivated stromal cells, and that this response was mediated by paracrine factors, thus minimizing the contribution of scaffolding effects [ 13, 14].
The most promising is to turn the coal into gas before it is burned, so that the carbon is separated, minimizing the contribution to global warming.
More recently, Henryon et al. [ 2] considered mating animals by minimizing the covariance between ancestral contributions (MCAC), which allows the impact of future changes in ancestral contributions to be less mutually dependent and favours the selection of animals with optimum contributions from their ancestors.
The intervention was delivered in a group format by CHWs in community-based settings and was overseen by registered dieticians employed by a local DEP, thereby minimizing the contributions of research resources and maximizing the responsibilities of community-based staff.
This was done by minimizing the lattice energy (Elatt), calculated as the sum of the intermolecular contribution (Uinter), and the conformational energy penalty (Δ Eintra) paid for distortion of the molecular geometry to improve the hydrogen bonding geometries.
Finally, the reported strategy to control protein aggregates provides robustness to cellular systems by minimizing the potentially harmful effects of aggregation-prone proteins and, at the same time, permits their vital contribution to the functioning of a cell.
To determine the optimum contribution of a priori information to the solution, the hyper-parameter was determined by minimizing the Akaike's Bayesian Information Criterion (ABIC) (Akaike 1980).
Friction Minimize friction on the axle by minimizing the contact surface area.
By design, fMRI methods attempt to minimize the contribution of variance from low-frequency physiological 1/f-noise.
