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This approach requires prior data on gene expression of large number of genes, generally determined by microarray technology or expressed sequence tags (ESTs).
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Gene expression in the whole cell can be routinely measured by microarray technologies or recently by using sequencing technologies.
A final example demonstrates the ability of the system to translate results identified by microarray technologies, or other related high throughput technologies, to identify likely Xenopus homologues.
Gene signatures derived by microarray technology play an important role in refining or supplementing existing diagnostic and prognostic factors such as staging systems (van de Vijver, 2002).
The basic rationale of normalization is to remove or adjust for artifacts caused by microarray technology rather than biological differences of the samples between printed probes.
The chapter outlines the human neurological diseases studied by microarray technology, such as multiple sclerosis, brain tumors, neuromuscular disorders, and alzheimer's disease.
In the last decade, comprehensive whole genome expression profiling by microarray technology has extensively defined breast cancer into distinct molecular subtypes that differ in terms of patient outcome and response to systemic treatment.
Current understanding of heart failure has been facilitated by microarray technology.
One of the main problems is the huge amount of data generated by microarray technology.
Future studies should be aimed at connecting these data directly to downstream gene-expression changes as measured by microarray technology.
More recently Carmichael and colleagues studied by microarray technology the genomic patterns in acute ICH (<24 hours) compared to healthy brains.
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