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These differences may be explained by methodological variations in the in vitro models used, suggesting that HAM was more affected by the experimental conditions.
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Conflicting findings across studies might be explained by methodological variations and by particular characteristics of the studied populations.
Non-vertebral fractures are infrequent events; their use as a trial endpoint requires large or high-risk populations and is affected by methodological variations (Miller 2008).
Differences between studies are likely due to methodological variations in regards to dose, route of administration and treatment duration.
This difference is most likely explained by the methodological variations, regional characteristics in marketed product ranges and by differences in classifying excipients into the toxicity categories.
The discrepant results of clinical follow-up studies are best explained by substantial methodological variations, study populations of insufficient size, and short periods of clinical follow up.
The minor variations in the predictions might reflect the methodological variations followed by different programs to identify signal peptides.
Despite these methodological variations, our annotations are in general agreement with the other annotations, as demonstrated by a >94% overlap in the number of identified genes and a significant number of identical features, such as the number of rRNA and tRNA genes, for both completed and draft genome sequences.
Part of the reason for the discrepant results of clinical follow-up studies is substantial methodological variation, resulting in a wide range of detection rates (4-48%) within comparable study populations [ 16]. *Prognostic value confirmed by multivariate analysis.
However, comparisons must be made with caution due to methodological variations between studies and gaps in the literature.
For the analysis of specific gene families, methodological variations were introduced as reported in text.
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