Sentence examples for by methodological problems including from inspiring English sources

Prior studies evaluating predictors of pain-related outcomes following treatment for sciatica have been limited by methodological problems, including retrospective study design, use of unvalidated outcome measures, and short-term follow-up periods.

Second, conclusions from the study of creatine supplementation in several myopathic conditions are deeply hampered by methodological problems including difficulties in statistical power due to rarity of diseases.

However, the studies were somewhat limited by methodological problems including small sample size and the use of assessment tools of limited validity [ 13].

7 Evidence about the determinants of obesity in children is sparse, largely because studies investigating the influence of obesogenic behaviours (such as low physical activity) have been limited by methodological problems including cross sectional designs, lack of power, and imprecise measurements of activity and adiposity.

The few existing candidate gene studies in PTSD have been limited by methodological problems including convenience samples, focus on chronic rather than lifetime PTSD cases, inadequate power, poorly matched controls and the failure to assay all common variation in genes examined.

10 These international studies, however, are limited by serious methodological problems including small sample sizes (or single-case studies), no control groups, limited outcome measures, and studies including both people with and without dementia.

Research investigating the influence of parenting has been hampered by several methodological problems including method variance, that is, reports of parenting and offspring's depressive symptoms are both derived from a single reporter, 15 reliance on small sample sizes, 16 cross-sectional design, 15 and relatively short follow-up periods of prospective studies.

The team were unable to reproduce the selection of cell lines used to establish the genomic signatures and noted methodological problems, including an "off-by-one" indexing error of probe set identification numbers, and the use of software that did not maintain independence of training and test sets.

Generally, cluster randomized trials, are susceptible to a range of methodological problems including selection bias [ 18].

Also, there was significant publication bias and other influential methodological problems including with self-rating, control condition and imputation.

This metaanalysis is limited by methodological problems in most included studies.