Sentence examples for by measuring expression changes from inspiring English sources
By measuring expression changes of tens of thousands of genes, we can identify mechanistic-relevant genes and pathways, improving our mechanistic understanding of toxicology.
The GSAS can illuminate which mechanisms are important in driving cancer growth by measuring expression change at a functional gene set level, as opposed to an individual gene level, where gene-gene interactions complicate the information that can be derived based on expression data.
In this study we examined the influence of genotoxicants on cerebellar function during early development by measuring global gene expression changes.
To better understand how aging changes gene expression patterns in a eukaryotic organism, and how these changes are affected by longevity, we measured gene expression changes in mianserin-treated or untreated C. elegans by RNA-sequencing (RNA-seq; Figure 1a).
The effects of such factors can be probed by measuring any changes in gene expression (Morley et al., 2004; Stranger et al., 2007; Emilsson et al., 2008).
Remodelling was estimated in each group by measuring the changes in protein expression of ALP and MMP9 at subchondral bone on week 22.
By measuring changes in gene expression after pathogen challenge, researchers may identify gene expression fingerprints that provide clues to molecular pathways involved in pathogen neutralization and/or removal, identify candidate genes controlling pathogen-specific immunity, and identify heritable differences in gene expression levels that correlate with disease resistance/susceptibility.
We also measured isoform expression changes by Cufflinks [ 51].
We knocked down the expression of ABL1 and/or ABL2 by shRNAs in LM2 cells and measured the expression changes in these BCLM-associated genes by RT-qPCR.
Microarrays are able to measure gene expression changes, but are limited by the availability of Expressed Sequence Tags (ESTs).
We have measured the expression changes induced by overexpression of the BCAR1 or BCAR3 gene in ZR-75-1 cells and have made direct comparisons with the expression changes after cell stimulation with oestrogen or epidermal growth factor (EGF).
