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Functional analysis of these genes by manipulating their expression using reverse genetic methods will provide important clues for understanding the MB-dependent brain functions.
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In the article, we make a comprehensive study of the contribution of the canonical TGFβ pathway actors during StC flattening by genetically manipulating their expression levels.
However, an understanding of the functional importance of lncRNAs in the context of the whole organism still relies on manipulating their expression by genetic modification, overexpression or knockdown strategies, and analysis of the resulting phenotypes.
Then, we manipulated their expression in NB cell lines by siRNA-mediated knock-down and forced over-expression of each gene under analysis.
We therefore tested whether they influence the CG15545-CRM driving GFP expression by manipulating their activity specifically during metamorphosis using the TARGET system [ 22].
They get the glue for their nests by manipulating their larvae in their claws until the babies excrete silk.
By manipulating their oxygen-carrying capacity, cheats can increase their stamina and speed.
Most people write by manipulating their fingers, what is called by some "drawing" the letters.
Sometimes, individuals attempt to control other people by manipulating their feelings of love.
Some of the benefits to working with zebrafish include their rapid development and the ease with which one can manipulate their gene expression by morpholino-based antisense oligonucleotides (Kari et al., 2007; Li et al., 2011).
An alternative could be exploring the plant's own defense mechanisms, by manipulating the expression of their endogenous defense proteins, or introducing an insect control gene derived from another plant.
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