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By manipulating levels of hippocampal neurogenesis, here we show that neurogenesis regulates this form of proactive interference.
Context: It has not been determined if a youth's reaction to the first smoking experience is predictive of future nicotine dependence, or whether the impact of the first cigarette can be altered by manipulating levels of tar, nicotine and menthol.
By manipulating levels of these proteins in sea slugs, the scientists were able to erase incidental memories that could trigger past traumas — a procedure that they say could one day provide relief to PTSD patients and others for whom seemingly mundane events, like hearing a dog bark or a door slam, can cause anxiety attacks.
Drosophila copper tolerance can be altered by manipulating levels of known copper uptake proteins or metallothioneins directly or via suppression of the metallothionein transcription factor, MTF-1 [13], [31], [31].
Moreover, origin specificity can be achieved by manipulating levels of ORC and competitor DNA.
Furthermore, resistance to this synthetic retinoid can be overcome by manipulating levels of cytotoxic SLs, creating opportunities for other alternative treatments.
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To this end, we attempted to manipulate levels of H3K27me3 by knocking down Ezh2, the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) (26).
We manipulated levels of testosterone (T) (by implantation; hormonal treatment or HTREAT) and parasites (through controlled infection; parasite treatment or PTREAT), and measured level of stress as evaluated by corticosterone (CORT) in feathers (Table 1).
To distinguish between these models, we manipulated levels of progeny production by controlling sperm availability.
To test this hypothesis, we specifically manipulated levels of mbCHCs.
By manipulating the levels of the molecule, known as NF-kB, within the hypothalamus, the researchers were able to slow down the rate of ageing and increase longevity of mice by up to 20 per cent.
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