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The role of these genes in the learning impairments associated with aging will ultimately have to be validated by manipulating gene expression in aged rats.
In addition, by manipulating gene expression during development, it was possible to significantly alter morphological sexual differentiation without a significant effect on adult life span.
Thus, a more convenient and less invasive methodology is needed to accelerate the study of glial function by manipulating gene expression in vivo.
An enzyme called LSD1 that controls the development of blood cells by manipulating gene expression in progenitor cells could be a therapeutic target for leukemia.
If StC were entirely passive during this process, it should be impossible to modulate this process, by manipulating gene expression in the soma, except if the genes encoded for direct cell shape regulators, such as Myosin, Actin, adhesion molecules etc.
Because of the prolonged human tooth development and differentiation, it may be necessary to accelerate the development of the grafted tooth germ by manipulating gene expression via local application of small inhibitory molecules and growth factors.
Similar(54)
Further analyses should be performed with larger experimental designs or by transgenic assays manipulating gene expression.
Yamanaka's method — based on manipulating gene expression — had initially been met with astonishment, but it soon fuelled a rapidly growing billion-dollar industry.
Recently miRNA have become very attractive tools in manipulating gene expression.
Thus, elucidating the mechanisms by which bacterial autoinducers manipulate gene expression in mammalian cells may yield new therapeutic approaches for abrogating bacterial infections.
For example, they have been used to manipulate gene expression by steric blocking of mature mRNA translation or by altering pre-mRNA splicing.
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