Sentence examples for by major differences in from inspiring English sources

However, while most of the regimens combining l-OHP and FU differ only marginally, the combinations of IRI and FU are characterised by major differences in terms of doses and schedules (Venook, 2005; O'Neil and Goldberg, 2005; Tournigand et al, 2004; Saltz et al, 2000; Douillard et al, 2000).

This cannot be explained by major differences in dissolved Si levels between HA-free and HA-containing clay systems (Fig. 1c).

Hence, it is unlikely that our western blot and enzyme activity results have been influenced by major differences in cellularity.

In addition, microarray analyses revealed that TP53- and ATM-mutant CLL share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.

However, efforts to make meaningful comparisons of micronutrient adequacy across European countries have been hampered not only by major differences in methods used in data collection, but also by disparities in data analysis.

While these findings may reflect true differences in the burden of neonatal infection and among resistance patterns, they may also be explained by major differences in data-collection methods.

Comparative studies of malaria interventions are always confounded by differences in background epidemiology between diverse study areas, but, in this case, the situation is made even more difficult by the major differences in design between the studies.

As reported by previous authors, major differences in biochemical composition relied on: (i) feeding behavior, in terms of filtration capacity and clearance rate (Vilela 1950; Heral et al. 1980); (ii) quality and quantity of seston available in the environment; (iii) state of sexual maturity of individuals (Fernández Reiriz et al. 2007).

By far, the major differences in gene expression in relation to the classification of subjects as HAT or LAT using the lipemic index (plasma ASP and TG) in this sample set are in SC adipose tissue.

By contrast, no major differences in cell-cycle stage or sub-G1 DNA content (a measure of apoptotic cell death) were evident in either replete medium or starvation conditions.

As the linear resolution is mainly governed by the stripe width, ultra-narrow stripes have been fabricated by FIB with no major differences in the quasi-static behavior down to widths of 150 nm.