Sentence examples for by maintaining the genomic from inspiring English sources

Under Trp53 +/− status, Rps27l acts as a tumor suppressor by maintaining the genomic stability and preventing Trp53 deletion.

Unexpectedly, we also found that Rps27l, under the Trp53 +/− background, acts as a tumor suppressor by maintaining the genomic integrity to prevent the loss of Trp53 heterozygosity and subsequent development of lymphoma.

DNA repair plays a critical role in protecting the genome from ultraviolet radiation and maintaining the genomic integrity of cells.

We anticipate being able to improve resolution and decrease the size of the genomic regions implicated by maintaining the AIL for many additional generations prior to QTL mapping and by adding markers to increase the number of informative recombination events across QTL intervals (see Macdonald and Long 2007).

Telomerase is a cellular enzyme that helps to provide genomic stability in tumor cells by maintaining the integrity of telomeres.

During reprogramming, Klf4 and c-Myc upregulate the expression of p53, a potential beneficial response by cells to maintain the genomic integrity under stress.

CRISPR/Cas9 technology would enable such studies by altering single SNPs in the genome of a model organism while maintaining the native genomic context of the variant.

Recent studies have now indicated that the role of caspase-2 may extend beyond apoptosis and that its tumor suppression function may, in part, be mediated by maintaining genomic stability and/or the oxidative stress response.

BRCA1 is also involved in maintaining the cell genomic integrity.

Conversely, DNA repair pathways delay cell senescence and aging by maintaining genomic integrity.

In addition, SIRT3 mediates cellular resistance toward various forms of stress by maintaining genomic stability and mitochondrial integrity.