Sentence examples for by low bone formation from inspiring English sources

Anabolic agents that inhibit sclerostin production or sclrostin binding to osteoblasts might offer specific targeted treatment for conditions characterized by low bone formation and elevated sclerostin.

These changes were accompanied by increased myostatin expression, low bone formation, and increased resorption.

RA is characterized by excessive bone degradation with relatively low bone formation targeting the small joints of the body in a symmetrical pattern [ 2, 4].

For instance, there is some preliminary evidence that women with PLO have low bone formation, suggesting that their bone-forming cells don't work properly.

We also found that low bone formation rates rather than increased bone resorption contributed to ostepenia in Pkd1+/Δ mice.

Bone biopsies from patients with PLS3 mutations have shown cortical and trabecular osteoporosis with normal to low bone formation rates.

In diabetic patients, osteoporosis is characterized by low bone turnover due to decreased bone formation [49]. Figure 1 summarizes the recommendations for the definition of osteoporosis in a toolbox.

Osteoporosis is a metabolic bone disorder defined as "a skeletal disease, characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture". 1 In the elderly, with decreasing levels of estrogen and testosterone, bone resorption exceeds bone formation; thus, the risk of osteoporosis increases.

During bone repair, bone remodeling involves bone resorption by osteoclasts, which is followed by bone formation by osteoblasts.

Bone homeostasis is maintained by a balance between bone resorption by osteoclasts and bone formation by osteoblasts.

Bone mass is maintained by continuous remodeling through repeated cycles of bone resorption by osteoclasts and bone formation by osteoblasts.