Sentence examples for by low activity of from inspiring English sources

Nevertheless, these bio-inspired strategies are limited by low activity of the oligopeptides compared to the native ligand due to the absence of complementary or modulatory domains.

In cellulosic biomass hydrolysis using Trichoderma cellulase system, cellobiose is accumulated by the dominant enzyme, cellobiohydrolase I that plays an important role for the hydrolysis of crystalline cellulose and by low activity of BGLs.

PPi formation is promoted by low activity of water in the system, for instance through low water-to-rock ratio (Russell & Hall, 1997).

Susceptibility to other triggers such as histamine, caused by impaired detoxification by low activity of di-amino-oxidase, may play an additional role and could be considered in the proposed diet.

Clotting of CRRT circuits could be caused by increased activation of coagulation, initiated either by the (intrinsic) contact activation pathway or the (extrinsic) tissue factor/activated factor VII (FVIIa) pathway, or by low activity of the endogenous anticoagulant pathways, such as the antithrombin system, the protein C/protein S system and the tissue factor pathway inhibitor system.

However, the biotransformation efficiency is hampered by the low activity of isoeugenol monooxygenase (IEM) and the product inhibition towards IEM.

In this study, using loss-of-function studies in vitro and in vivo, we show that the anti-apoptotic protein poly(ADP-ribose) polymerase (PARP 14 promotes aerobic glycolysis in human hepatocellular carcinoma (HCC) by maintaining low activity of the pyruvate kinase M2 isoform (PKM2), a key regulator of the Warburg effect.

The two-step coating design was essential for achieving a high degree of transfection, as evidenced by the low activity of NPs modified with the same amount of R8 in a regular single-coated design.

This could be explained by the low activity of the GH/IGF1/MTOR pathway, consistent with the "within species" rule.

Since as we have shown the G1/S checkpoint is seriously compromised by the low activity of Rb with the concomitant increase in E2F activity, HGUE-C-1 cells will be able to proliferate in such conditions.

At sub- KM nitrite concentrations, the catalytic wave is dominated by a single feature, Ecat1, which is nearly indistinguishable from the nonturnover signal caused by the low activity of this mutant.