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Three weeks after BDL, rats developed biliary fibrosis which was supported by liver function tests, ammonia levels, and hydroxyproline content.
Effect of chronic arsenic exposure on liver was determined by liver function tests.
Another study [ 39] of arsenic-endemic and non-endemic population in India showed that arsenic elevated the activity of blood proteins/enzymes assessed by liver function tests.
Exclusion criteria included a fasting plasma glucose of 13.3 mmol/L; hepatic dysfunction as indicated by liver function tests more than three times the upper limit of normal; myocardial infarction; stroke or transient ischemia within the previous 3 months; or treatment with other antidiabetic agents except those noted above.
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AEs associated with hepatic toxicity are identified by liver function testing, and patients receiving TKI therapy should be queried regarding their use of other hepatotoxic agents.
Nevertheless, administration of allopurinol or febuxostat to a gout population with significant rates of obesity, metabolic syndrome, and alcohol use [ 34, 35] is accompanied by liver function test abnormalities more frequently than is placebo administration [ 35].
Male Wistar rats subjected to BDL developed biliary fibrosis after four weeks which was supported by altered liver function tests, increased ammonia levels and histological staining (Sirius red).
Study design: A retrospective review of a conservative regime using intravenous magnesium sulfate, glucocorticoids and antihypertensive drugs, monitored by serial liver function tests, full blood count, coagulation profile, and renal function tests.
All but one (F2) were diagnosed with cirrhosis by standard liver function tests and biopsy.
In accordance, Kramer and colleagues could not predict citrate clearance by standard liver function tests [ 23].
Suspicion of metachronous disease may be prompted by abnormal liver function tests or elevated carcinoembryonic antigen (CEA).
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