Sentence examples for by linkage analysis to from inspiring English sources

Furthermore, the gene has been mapped by linkage analysis to SSC 3 [ 43].

In 1990, the first breast cancer susceptibility gene, BRCA1, was localised by linkage analysis to chromosome 17q21 [ 9].

The FSHD locus has been mapped by linkage analysis to the subtelomeric region of the long arm of chromosome 4 (4q35) [ 2, 3].

WDM is an autosomal dominant disorder characterized by distal limb weakness, which was previously associated by linkage analysis to a region on chromosome 2 (26).

Interestingly, the human PLS1 gene maps to 3q23, and this chromosomal region has been associated by linkage analysis to progressive forms of hearing impairment in the elderly (55).

GNE encodes a bifunctional enzyme (UDP-N-acetylglucosamine 2-epimerase/N-acetlymannosamine kinase) in the biosynthetic pathway of sialic acid, and was identified by linkage analysis to be mutated in hereditary inclusion body myopathy (HIBM).

The minimal genetic interval inferred by linkage analysis at Carg3 extends over 40 Mb, while that at Carg4 is 30 Mb.

Both GUJ0039 and GUJ0025 were genotyped on the ChickRH6 panel [ 20] and were found by two-point linkage analysis to co-segregate with markers belonging to GGA18 and GGAZ, respectively [ 21].

It is important to note that the estimate of δ was sensitive to the estimated power to detect cis-acting QTL by linkage analysis and to a lesser extent to the estimated false-positive rate.

Association analysis has traditionally been used to home in on regions that were identified by linkage analysis or to test for association with specific genes that were strong candidates because their function was known.

The identity-by-descent matrix was calculated by linkage analysis using one to five generations of pedigree data.