Sentence examples for by linkage analysis and from inspiring English sources

The present study identified a new, broad-spectrum BPH resistance gene, BPH31 that was located on the long arm of chromosome 3 by linkage analysis and fine-mapping strategies.

It is important to note that the estimate of δ was sensitive to the estimated power to detect cis-acting QTL by linkage analysis and to a lesser extent to the estimated false-positive rate.

These QTLs were detected by linkage analysis and by candidate gene analysis.

In this study, the authors have also first carried out mapping by linkage analysis and finally ended up with LDL analyses and multiple LRT peaks.

By linkage analysis and exon sequencing, the authors identified a heterozygous missense mutation in GUCY2C, encoding the guanylate cyclase C receptor, which is involved in intestinal secretion.

Further, positions for 130 previously unpositioned contigs from assembly of the bovine genome sequence (Btau_4.0) found using comparative sequence analysis were validated by linkage analysis, and 28% of these positions corresponded to extreme values of population recombination rate.

More importantly, an association of the ITPKC (inositol 1,4,5-trisphosphate 3-kinase C) gene region with KD susceptibility was identified by linkage analysis in Japanese and US cohorts, and the encoded protein was shown to be involved in T-cell activation in an in vitro cell system [12].

Beside these two polymorphisms of the PGC- 1α and the PPAR- γ genes (rs8192673 and rs1801282) several other genes have been so far implicated by linkage analysis, association studies, and genome-wide association studies in the development of obesity and obesity-associated phenotypes [ 32- 38].

QTL detection was performed by linkage analysis using GridQTL and QTLMap.

The candidate region on SSC15 has been confirmed by linkage analysis but molecular and functional analyses have excluded that the mutated phenotype is caused by structural mutations in or ablation of any of the two candidate genes.

This QTL vanished by linkage analysis of subgroups 2 and 3. Interestingly, the linkage analysis with two subgroups 2 and 3 suggested an AF QTL at 102 cM on GGA5.