Sentence examples for by limiting the expression from inspiring English sources
Therefore, NMD activity may interfere with anti-tumor immunity by limiting the expression of some of these aberrant proteins.
In a previous study, we confirmed this prediction through the experimental removal of female selection pressures in Drosophila melanogaster, achieved by limiting the expression of all major chromosomes to males.
To test this idea, we recorded the airflow response from the β lobe and the β' lobe separately by limiting the expression of G-CaMP to either α/β or α'/β' neurons using α/β neuron specific Gal4 line c739 [37] or α'/β' neuron specific Gal4 line g0050 [32].
We show that hairy functions in the muscle to refine the terminal cell fate to a single cell at the tip of the dorsal branch by limiting the expression domain of branchless (bnl), encoding the FGF ligand, in surrounding muscle cells.
Moreover, BBR also failed to affect the Gli-luciferase activity provoked by limiting the expression of Sufu (Fig. 3b), a negative regulator of Hh signaling pathway [ 28], suggesting that BBR inhibited the Hh pathway activity by acting upstream of Sufu.
By limiting the expression of Yap to a small number of cells, this study reveals a new level of complexity for the role of Yap in tissue homeostasis that has been thus far so unappreciated.
In an idiosyncratic ruling, Belobaba found that the province's proposal to rearrange the playing field during an election violates section 2(b) of the Charter of Rights and Freedoms by limiting the free expression of Torontonian voters.
In alignment with the results obtained by the pharmacological tool SP, limiting the expression of JNK1/2 led to increase the expression of epithelial marker E-cadherin and to decrease the expression of mesenchymal markers N-cadherin, vimentin, when compared to that of the KB/VCR cells infected with shRNA control.
In that case, it was found that the formation of a Pbx-Hox-Meis/Prep ternary complex on Pbx-Hox and Meis sites within this enhancer could be restricted by the binding of a Pbx1-Prep1 hetorodimer to a nearby site, thus limiting the expression driven by this enhancer to r4.
Our studies demonstrate a novel role for Hairy in restriction of the terminal cell fate by limiting the domain of bnl expression in surrounding muscle cells such that only a single dorsal branch cell becomes specified as a terminal cell.
Generally open chromatin increases the accessibility of the genome to transcription machinery, while closed chromatin represses gene expression by limiting the accessibility [ 14, 22, 24].
