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Thus, measures from diffusion weighted imaging, such as fractional anisotropy, can be used to assess fibre integrity and have been postulated as sensitive markers for overall tumour extent ; however, research has so far been hampered by limitations in data analysis.
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Although there was imperfect agreement between the data sources, some of this could be explained by limitations in the administrative data or in data linkage, rather than inaccurate self-report.
Hence, the apparent lack of association may also have been impacted by the limitations in data availability.
Furthermore, critical appraisal of the very few prospective studies is hampered by limitations in design or insufficient data given by the authors.
Progress in elucidating the mechanism and role of intercellular ice propagation in tissue freezing has been hampered in part by limitations in experimental design and data analysis.
Comparing groups of early deaths and long survivors minimizes errors introduced by limitations in the available survival data and by deaths not directly attributable to cancer progression.
With modern 3D imaging techniques, such as HREM, accurate and reproducible phenotyping is not constrained by limitations in the available image data.
Highest confidence relationship classifications were those for which all methods were congruent, rendering our approach conservative in order to minimize error introduced by limitations in sampling (absence of parental data) and the limited power of our set of genetic markers for distinguishing adjacent relationship categories.
L index results might be affected, other than by uncertainty on input data, by limitations in capturing some dynamic changes occurring in the ecosystem [10].
But serious limitations in data collection mean that the report serves as a barometer and not a comprehensive overview.
25, 26 The lack of association between AEs and HSUVs may also be partly explained by a limitation in data collection in NCT00753545.
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