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The predominant and persistent expression of the anterior markers was accompanied by lack of expression of EN1 and HOXB4, two transcriptional factors expressed in the mid/hind-brain and spinal cord cells, as assayed by RT-PCR (Figure 3B).
It is caused by lack of expression of the UBE3A gene on the maternal chromosome 15q11-q13.
This inactivation can be caused by lack of expression due to deletion or promoter silencing.
PWS is caused by lack of expression of imprinted genes in a ∼4 mb region of chromosome band 15q11.2.
Recently it was shown that CD27 down-regulation can be blocked by lack of expression of its ligand, CD70 [22] which requires both antigen and cytokines, including IL-2 for expression.
As shown in Figure 2, co-culture of NK cells with immature pDC that were isolated from healthy controls or HIV-1 patients resulted in minimal activation of NK cells as assessed by lack of expression of CD69, HLA-DR, and CD25.
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Therefore, we verified the expression of the caudal transcription factor HOXB9 (Fig. 1e) and confirmed immunolabelling specificity by lack of HOXB9 expression in NCX-NES cells (Supplementary Fig. 1d).
Comparison of the two mutant strains with each other and with the WT strain (C57BL/6J) reveals the genes truly affected by lack of Chrnb2 expression vs. those resulting from inter-strain differences.
AS can be caused either by lack of UBE3A expression or by mutations in UBE3A.
Quiescent tumor cells are found in vivo and can be detected by lack of Ki67 expression.
In addition, CD133+ cells are characterised in situ by lack of CK20 expression, whereas they are positive for EpCAM.
More suggestions(15)
by lack of ambition
by likelihood of expression
by way of expression
by lack of leadership
by supplementation of expression
by choice of expression
by phase of expression
by lack of publicity
by lack of access
by objectivity of expression
by virtue of expression
by lack of space
by lack of resolve
by lack of information
by introduction of expression
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