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According to previous report 25, we also found that in these positive tumors, two subtypes could be distinguished by its staining pattern and percentage of stained nuclei; "aberrant type" and "scattered type".
This study attempted to find a new definition of p53 staining by its staining pattern.
Here, we report a new discrimination on immunohistochemistry staining of p53 by its staining pattern.
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In this study, we reevaluated the p53-positive tumors to two groups by its staining patterns.
Our study showed that positive staining of p53 has two types by its staining patterns in gastric cancer.
Due to the intracellular vesicular localization of the CD68 receptor, it was not possible to directly assess the morphology of the cell expressing it by means of its staining pattern (Figure 5B).
Strikingly, the WT ECD predominantly co-localized with Mitotracker (a mitochondria-specific dye), whereas the finger mutant ECD partially lost this ability as judged by its diffuse staining pattern (Supplementary information, Figure S7A).
Intracellular parasites were identified by the staining pattern of the T. gondii protein GRA7.
In interpretation of p53 immunohistochemistry staining, discriminating p53-positive tumors by their staining pattern is important in gastric cancer.
In interpretation of p53 immunohistochemistry staining, distinguishing p53-positive tumors by their staining pattern may be important in gastric cancer.
The intestinal type of pancreatic ductal adenocarcinoma was not associated with intraductal papillary mucinous neoplasm and could not be reliably diagnosed by immunohistochemical staining pattern alone.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com