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Methylation at this intronic CGI did not silence GNA11 as demonstrated by its robust expression in RKO cells (Figure 2c).
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It seems likely that Siglec-H has similar postnatal immunological functions as other Siglecs, given its robust expression in spleen.
All of these are enabled by its robust software.
Reset cells and ESC form a distinct cluster characterized by the robust expression of naive markers including NANOG, KLF4, and TFCP2L1.
The peak stage of ARI is defined by the robust expression of proinflammatory-associated genes and coincides with the greatest severity of ARI symptoms.
Interestingly, the dynamics of Fkbp5 induction by Dex, characterized by a substantial post-exposure delay followed by a robust expression, is reminiscent of the C-FFL in which the jointly regulated gene is activated by both the master and intermediate TFs [ 12].
Abdul-Hafez et al. demonstrated that the transition of normal lung fibroblasts to myofibroblasts by TGF-β1 in vitro is accompanied by robust expression of angiotensin mRNA, protein, and AngII peptide [ 56].
DV boundary establishment and maintenance is pointed out by robust expression of active Notch, and also by the formation of a Wg morphogen gradient towards both compartments of the disc (data not shown).
This is reflected by robust expression of human UCN3 but lack of enrichment in either human islet cell type.
Five weeks after BMT, hematopoietic reconstruction of recipient mice were confirmed by robust expression of GFP (83.0 ± 4.2%) and CD45 (93.4 ± 5.2%) in peripheral blood by FACS analysis.
Moreover, immunohistochemistry showed that human degenerative disc samples with each grade had a high proportion of nitrotyrosine-positive cells, accompanied by robust expression of TNFα and IL-1β, whereas human healthy disc had low expression of these markers (Fig. 1g).
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